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2.3.1.246: 3,5-dihydroxyphenylacetyl-CoA synthase

This is an abbreviated version!
For detailed information about 3,5-dihydroxyphenylacetyl-CoA synthase, go to the full flat file.

Reaction

4 malonyl-CoA =

(3,5-dihydroxyphenylacetyl)-CoA
+ 3 CoA + 4 CO2 +
H2O

Synonyms

dpgA

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.246 3,5-dihydroxyphenylacetyl-CoA synthase

General Information

General Information on EC 2.3.1.246 - 3,5-dihydroxyphenylacetyl-CoA synthase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
inactivation of dpgA results in loss of balhimycin production, and restoration is achieved by supplementation with 3,5-dihydroxyphenylacetate
physiological function
the enzyme is involved in the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin