2.3.1.246: 3,5-dihydroxyphenylacetyl-CoA synthase
This is an abbreviated version!
For detailed information about 3,5-dihydroxyphenylacetyl-CoA synthase, go to the full flat file.
Reaction
4 malonyl-CoA = + 3 CoA + 4 CO2 +
Synonyms
dpgA
ECTree
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General Information
General Information on EC 2.3.1.246 - 3,5-dihydroxyphenylacetyl-CoA synthase
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malfunction
inactivation of dpgA results in loss of balhimycin production, and restoration is achieved by supplementation with 3,5-dihydroxyphenylacetate
physiological function
the enzyme is involved in the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine, a component of the vancomycin-type antibiotic balhimycin