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2.3.1.198: glycerol-3-phosphate 2-O-acyltransferase

This is an abbreviated version!
For detailed information about glycerol-3-phosphate 2-O-acyltransferase, go to the full flat file.

Word Map on EC 2.3.1.198

Reaction

an acyl-CoA
+
sn-glycerol 3-phosphate
=
CoA
+
a 2-acyl-sn-glycerol 3-phosphate

Synonyms

AT1G01610, At2g38110, AtGPAT4, AtGPAT6, glycerol-3-phosphate 2-O-acyltransferases, glycerol-3-phosphate acyltransferase, glycerol-3-phosphate acyltransferase 6, GPAT4, GPAT5, GPAT6, GPAT8, More, NbGPAT6a, PpGPAT2, PpGPAT4, SlGPAT6, SlGPAT6a, sn-2 acyltransferase, sn-2 GPAT, sn-2-GPAT, sn-glycerol-3-phosphate acyltransferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.198 glycerol-3-phosphate 2-O-acyltransferase

Engineering

Engineering on EC 2.3.1.198 - glycerol-3-phosphate 2-O-acyltransferase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G163R
isolation of a set of fruit brightness mutants (named glossy mutants) with abnormal fruit cutin amounts/compositions from the EMS-mutagenized tomato mutant population (cv Micro-Tom). The glossy mutant line P23F12 exhibits enhanced fruit brightness and a reduced cutin load. Whole-genome sequencing and gene mapping show that a single G613A nucleotide transition in the first exon leading to a G163R nonsynonymous mutation in gene SlGPAT (Solyc09g014350) is responsible for the mutant glossy fruit phenotype, i.e. mutant gpat6-a, overview. The inactive mutant gpat6-a has a fruit cuticle that shows reduced levels of C16 cutin monomers. No differences are observed in total wax load between wild-type and gpat6-a fruits, but differences in wax composition are apparent, such as increased or decreased levels of several minor C25 to C30 alkanes in the gpat6-a mutant. Since both even- and odd-numbered alkanes display similar trends, these variations are likely independent of the alkane biosynthetic pathways. The most striking wax compositional change in the gpat6-a mutant is an approximately 5fold increase in delta- and alpha-amyrin levels and to a lesser extent in beta-amyrin levels. In contrast to waxes, the total cutin load in gpat6-a is reduced by almost 3fold. MapMan-based general overview of genes differentially expressed between wild-type and gpat6-a mutant fruit
additional information