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2.3.1.151: 2,3',4,6-tetrahydroxybenzophenone synthase

This is an abbreviated version!
For detailed information about 2,3',4,6-tetrahydroxybenzophenone synthase, go to the full flat file.

Word Map on EC 2.3.1.151

Reaction

3 Malonyl-CoA +

3-hydroxybenzoyl-CoA
= 4 CoA +
2,3',4,6-tetrahydroxybenzophenone
 + 3 CO2

Synonyms

2,3',4,6-Tetrahydroxybenzophenone synthase, benzophenone synthase, BPS, More, Synthase, benzophenone

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.151 2,3',4,6-tetrahydroxybenzophenone synthase

Cloned

Cloned on EC 2.3.1.151 - 2,3',4,6-tetrahydroxybenzophenone synthase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
construction of cDNA library, DNA and amino acid sequence determination and analysis, functional overexpression of wild-type enzyme and expression of mutant enzymes in Escherichia coli strain BL21(DE3) as GST fusion protein
-
DNA and amino acid sequence determination and analysis, sequence comparison and phylogenetic tree, expression of C-terminally His-tagged BPS in Escherichia coli
expressed in Escherichia coli
-
two cDNAs are isolated and heterologously expressed but both enzymes are inactive
-
wild-type benzophenone synthase and enzyme mutants are heterologously expressed as N-terminally His6-tagged proteins in Escherichia coli
-