2.3.1.136: polysialic-acid O-acetyltransferase

This is an abbreviated version!
For detailed information about polysialic-acid O-acetyltransferase, go to the full flat file.

Reaction

Synonyms

lecithin:retinol acyltransferase, LRAT, NeuO, OatC, OatWY, polySia specific O-acetyltransferase, polysialic acid O-acetyltransferase, polysialic acid O-AcTase, polysialic acid specific O-acetyltransferase, polysialic acid-specific O-acetyltransferase, polysialic-acid O-acetyltransferase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.136 polysialic-acid O-acetyltransferase

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Results	in table
32	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
1	Cofactor
2	Crystallization (Commentary)
3	General Information
3	General Stability
1	Inhibitors
2	kcat/KM [mM/s]
12	KM Value [mM]
1	Localization
1	Metals/Ions
4	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
17	Organism
3	PDB ID
5	pH Optimum
28	Protein Variants
5	Purification (Commentary)
2	Reaction
1	Reaction Type
10	Reference
1	Specific Activity [micromol/min/mg]
1	Storage Stability
24	Substrates and Products (Substrate)
7	Subunits
17	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
11	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.136 - polysialic-acid O-acetyltransferase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

acetyl-CoA + an alpha-2,8-linked polymer of sialic acid

CoA + silaic acid acetylated at O-7 or O-9

2 entries

acetyl-CoA + sialic acid polymer of length 12-14

CoA + O-acetyl sialic acid polymer

Escherichia coli

-

-

486289

-

-

?

additional information

?

-

2 entries

acetyl-CoA + an alpha-2,8-linked polymer of sialic acid

CoA + silaic acid acetylated at O-7 or O-9

Escherichia coli

Q58WP5

-

660391

-

-

?

acetyl-CoA + an alpha-2,8-linked polymer of sialic acid

CoA + silaic acid acetylated at O-7 or O-9

Escherichia coli RS174

Q58WP5

-

660391

-

-

?

additional information

?

-

Escherichia coli

-

polysialic-acid O-acetyltransferase is responsible for the majority of bacterial capsule modification that takes place in vivo. In addition, there exists a minor polysialic-acid O-acetyltransferase independent pathway involving O-acetylation of monomeric sialic acid

674296

-

-

?

additional information

?

-

Escherichia coli K1

-

polysialic-acid O-acetyltransferase is responsible for the majority of bacterial capsule modification that takes place in vivo. In addition, there exists a minor polysialic-acid O-acetyltransferase independent pathway involving O-acetylation of monomeric sialic acid

674296

-

-

?