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2.3.1.136: polysialic-acid O-acetyltransferase

This is an abbreviated version!
For detailed information about polysialic-acid O-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.136

Reaction

acetyl-CoA
+
an alpha-2,8-linked polymer of sialic acid
=
CoA
+
polysialic acid acetylated at O-7 or O-9

Synonyms

lecithin:retinol acyltransferase, LRAT, NeuO, OatC, OatWY, polySia specific O-acetyltransferase, polysialic acid O-acetyltransferase, polysialic acid O-AcTase, polysialic acid specific O-acetyltransferase, polysialic acid-specific O-acetyltransferase, polysialic-acid O-acetyltransferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.136 polysialic-acid O-acetyltransferase

Cloned

Cloned on EC 2.3.1.136 - polysialic-acid O-acetyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in Escherichia coli as a C-terminal hexahistidine tagged fusion protein
-
expressed in Escherichia coli as a C-terminal hexahistidine-tagged fusion protein
-
expressed in Escherichia coli as a His-tagged fusion protein
expression of the engineered C-terminally His6-tagged NeuO mutant in Escherichia coli strain BL21 gold (DE3)
-
gene neuO, allelic variants, DNA and amino acid sequence determination and analysis, the enzyme is genetically linked to the endo-neuraminidase tail protein gene of a chromosomal accretion element CUS-3, genetic structure, role of heptanucleotide repeat regions, overview
Q58WP5