2.3.1.117: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

This is an abbreviated version!
For detailed information about 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, go to the full flat file.

Word Map on EC 2.3.1.117

2.3.1.117

l-lysine

meso-diaminopimelate

diaminopimelate

trimer

glutamicum

left-handed

peptidoglycan

corynebacterium

beta-helix

tuberculosis

desuccinylase

succinylated

hexapeptide

dihydrodipicolinate

lbetah

Reaction

(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate

Synonyms

DapD, Mtb-DapD, PA3666, succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase, succinyltransferase, tetrahydrodipicolinate, TabB, tetrahydrodipicolinate N-succinyltransferase, tetrahydrodipicolinate succinylase, tetrahydrodipicolinate succinyltransferase, tetrahydrodipicolinate-N-succinyltransferase, THDP

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.117 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

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Results	in table
21566	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
1	Cofactor
9	Crystallization (Commentary)
3	General Information
1	General Stability
1	IC50 Value
23	Inhibitors
2	kcat/KM [mM/s]
3	Ki Value [mM]
9	KM Value [mM]
5	Metals/Ions
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
15	Organism
6	Pathway
58	PDB ID
2	pH Optimum
1	pH Range
3	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
1	Specific Activity [micromol/min/mg]
2	Storage Stability
22	Substrates and Products (Substrate)
4	Subunits
17	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.3.1.117 - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

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succinyl-CoA + (2S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylic acid

CoA + (2S)-2-[(3-carboxypropanoyl)amino]-6-oxoheptanedioic acid

7 entries

succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O

CoA + N-succinyl-L-2-amino-6-oxoheptanedioate

Pseudomonas aeruginosa

the enzyme is absolutely specific for the L-2-aminopimelate enantiomer

720852