2.1.1.B74: apigenin 7-O-methyltransferase

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For detailed information about apigenin 7-O-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.B74

2.1.1.B74

quercetin

poplar

regioselectivity

luteolin

flavonols

genkwanin

7-hydroxyl

kaempferol

synthesis

Reaction

Synonyms

F1-OMT, F7OMT, flavone 7-O-methyltransferase, flavonoid 7-O-methyltransferase, flavonoid 7-OMT, POMT-7, POMT7

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.B74 apigenin 7-O-methyltransferase

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Results	in table
2	AA Sequence
1	Application
4	Cloned(Commentary)
2	Cofactor
1	General Information
2	KM Value [mM]
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
4	Organism
2	pH Optimum
1	Protein Variants
1	Purification (Commentary)
1	Reaction
4	Reference
2	Source Tissue
9	Substrates and Products (Substrate)
1	Subunits
9	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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synthesis

Ocimum basilicum

K0I977

expression together with basil flavonoid 6-hydroxylase encoded by CYP82D33 and further ethyltransferases in Saccharomyces cerevisiae to produce 8- and/or 6-substituted, methoxylated flavones from their natural precursor apigenin. The yeast cells produce substantial amounts of 6-hydroxylated, methylated derivatives of naringenin and luteolin while the corresponding derivatives of flavonol kaempferol are only detected in trace amounts. The substrate specificity of both the hydroxylases and the flavonoid O-methyltransferases is limiting yields obtained with alternative substrates

755873