2.1.1.35: tRNA (uracil54-C5)-methyltransferase
This is an abbreviated version!
For detailed information about tRNA (uracil54-C5)-methyltransferase, go to the full flat file.
Word Map on EC 2.1.1.35
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2.1.1.35
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histone
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h3k4me3
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trithorax
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trimethylation
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compass
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prdi-bf1
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molecular biology
- 2.1.1.35
- histone
-
h3k4me3
-
trithorax
-
trimethylation
- compass
-
prdi-bf1
- molecular biology
Reaction
Synonyms
5-methyluridine 54 tRNA methyltransferase, m5U 54 tRNA methyltransferase, m5U 54 tRNA MTase, m5U methyltransferase, m5U-methyltransferase, methyltransferase, transfer ribonucleate uracil 5-, PAB0719, PAB0719 enzyme, PabTrmU54, ribothymidyl synthase, rTase, RumA, RumA-type tRNA(uracil-54, C5)-methyltransferase, RUMT, S-adenosyl-L-methionine-dependent tRNA (uracil-54, C5)-methyltransferase, transfer RNA uracil 5-methyltransferase, transfer RNA uracil methylase, TrmA, TRMT2A, tRNA (uracil-54, C5)-methyltransferase, tRNA uracil 5-methyltransferase, tRNA(m5U54)methyltransferase, tRNA(uracil-5-)methyltransferase
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General Information
General Information on EC 2.1.1.35 - tRNA (uracil54-C5)-methyltransferase
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physiological function
TRMT2A is responsible for the majority of m5U present in human RNA, it commonly targets U54 of cytosolic tRNAs. In both HAP-1 and HEK-293 TRMT2A knockout cell lines, the majority of m5U signal present in total RNA from control cell lines is absent