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2.1.1.317: sphingolipid C9-methyltransferase

This is an abbreviated version!
For detailed information about sphingolipid C9-methyltransferase, go to the full flat file.

Reaction

S-adenosyl-L-methionine
+
a (4E,8E)-sphinga-4,8-dienine ceramide
=
S-adenosyl-L-homocysteine
+
a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide

Synonyms

C9-methyltransferase for sphingolipid 1, MTS1, SMT1, smtA, SmtB

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.1 Methyltransferases
                2.1.1.317 sphingolipid C9-methyltransferase

Systematic Name

Systematic Name on EC 2.1.1.317 - sphingolipid C9-methyltransferase

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SYSTEMATIC NAME
IUBMB Comments
S-adenosyl-L-methionine:(4E,8E)-sphinga-4,8-dienine ceramide C-methyltransferase
The enzyme, characterized from the fungi Komagataella pastoris and Fusarium graminearum, acts only on ceramides and has no activity with free sphingoid bases or glucosylceramides.