2.1.1.317: sphingolipid C9-methyltransferase

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For detailed information about sphingolipid C9-methyltransferase, go to the full flat file.

Reaction

a 9-methyl-(4E,8E)-sphinga-4,8-dienine ceramide

Synonyms

C9-methyltransferase for sphingolipid 1, MTS1, SMT1, smtA, SmtB

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.317 sphingolipid C9-methyltransferase

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Results	in table
10	AA Sequence
3	Cloned(Commentary)
2	Cofactor
22	General Information
2	Localization
3	Natural Substrates/ Products (Substrates)
15	Organism
5	Protein Variants
1	Reaction
7	Reference
3	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name

Cloned

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Cloned on EC 2.1.1.317 - sphingolipid C9-methyltransferase

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Go to Cloned (commentary) Search

DNA and amino acid sequence determination and analysis, genetic organization and clustering of SAM-dependent methyltransferase sequences, phylogenetic tree, recombinant enzyme functional expression in a Saccharomyces cerevisiae strain that is engineered to produce glucosylceramides suitable as a substrate for C9-methylation. C9-methylated sphingolipids are detected in the transformed strain expressing the candidate from Pichia pastoris, demonstrating its function as a sphingolipid C9-methyltransferase

Komagataella pastoris

Q2QJ12

734154

gene mts1, orf19.4831, cloning in Escherichia coli strain DH5alpha

Candida albicans

734640

genes FgMT1 and FgMT2, DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression in and complementation of an enzyme knockout mutant strain C-9-MT-null of Pichia pastoris

Fusarium graminearum

733757