2.1.1.225: tRNA:m4X modification enzyme

This is an abbreviated version!
For detailed information about tRNA:m4X modification enzyme, go to the full flat file.

TRM13, Trm13p, tRNA:Xm4 modification enzyme

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Results	in table
2514	AA Sequence
1	Cloned(Commentary)
1	General Information
1	kcat/KM [mM/s]
1	KM Value [mM]
3	Natural Substrates/ Products (Substrates)
2	Organism
1	Pathway
1	pH Optimum
1	Purification (Commentary)
6	Reaction
2	Reference
7	Substrates and Products (Substrate)
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

Natural Substrates Products on EC 2.1.1.225 - tRNA:m4X modification enzyme

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S-adenosyl-L-methionine + adenosine4 in tRNAHis

S-adenosyl-L-homocysteine + 2'-O-methyladenosine4 in tRNAHis

the enzyme is necessary and sufficient for 2'-O-methylation at position 4 of yeast tRNA. 2'-O-methylation in the acceptor stem of tRNA

S-adenosyl-L-methionine + cytidine4 in tRNAGly(GCC)

S-adenosyl-L-homocysteine + 2'-O-methylcytidine4 in tRNAGly(GCC)

the enzyme is necessary and sufficient for 2'-O-methylation at position 4 of yeast tRNA. 2'-O-methylation in the acceptor stem of tRNA

S-adenosyl-L-methionine + cytidine4 in tRNAPro

S-adenosyl-L-homocysteine + 2'-O-methylcytidine4 in tRNAPro

the enzyme is necessary and sufficient for 2'-O-methylation at position 4 of yeast tRNA. 2'-O-methylation in the acceptor stem of tRNA