2.1.1.139: 3'-demethylstaurosporine O-methyltransferase This is an abbreviated version! For detailed information about 3'-demethylstaurosporine O-methyltransferase, go to the full flat file .
Reaction
S-adenosyl-L-methionine +
3'-demethylstaurosporine =
S-adenosyl-L-homocysteine +
staurosporine
Synonyms 3'-demethoxy-3'-hydroxystaurosporine O-methyltransferase, staurosporine synthase
ECTree
Systematic Name
Systematic Name on EC 2.1.1.139 - 3'-demethylstaurosporine O-methyltransferase
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S-adenosyl-L-methionine:3'-demethylstaurosporine O-methyltransferase
Catalyses the final step in the biosynthesis of staurosporine, an alkaloidal antibiotic that is a potent inhibitor of protein kinases, especially protein kinase C.