1.8.3.2: thiol oxidase This is an abbreviated version! For detailed information about thiol oxidase, go to the full flat file .
Word Map on EC 1.8.3.2
Reaction
2 R'C(R)SH
+
O2 =
R'C(R)S-S(R)CR' +
H2O2
Synonyms Ac92, AcMNPV P33, ALR, ALRp, AtSOX, augmenter of liver regeneration, DTT-oxidase, E10R, egg white oxidase, Ero1, Ero1p, ERV/ALR sulfhydryl oxidase, Erv1, Erv1p, Erv2, ERv2p, FAD-linked sulfhydryl oxidase, FAD-linked sulfhydryl oxidase ALR, FAD-sulfhydryl oxidase, flavin adenine dinucleotide-linked sulfhydryl oxidase, flavin-dependent sulfhydryl oxidase, GmQSOX1, GmQSOX2, hepatic regenerative stimulator substance, hepatopoietin, mitochondrial FAD-linked sulfhydryl oxidase ERV1, More, neuroblastoma-derived sulfhydryl oxidase, oxidase, thiol, P33, pB119L, protein pB119L, QSCN6, QSOX, QSOx1, QSOX1b, QSOX2, QSOX3, Quiescin Q6, quiescin Q6 sulfhydryl oxidase, quiescin Q6 sulfhydryl oxidase 1, quiescin Q6/sulfhydryl oxidase, quiescin sulfhydryl oxidase, quiescin sulfhydryl oxidase 1, quiescin sulhydryl oxidase, quiescin-like flavin-dependent sulfhydryl oxidase, Quiescin-sulfhydryl oxidase, quiescin/sulfhydryl oxidase, quiescin/sulfhydryl oxidase 1b, quiescin/sulphydryl oxidase, rQSOX, sfALR, SOX, Sox1, Sox2, SOXN, sulfhydryl oxidase, sulfhydryl oxidase SOx-3, sulfhydryl oxidase, P33, sulphydryl oxidase, thiol oxidase Erv1, thiooxidase
ECTree
Source Tissue
Source Tissue on EC 1.8.3.2 - thiol oxidase
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expression analysis of a panel of cDNAs derived from 50 clinically-graded normal and malignant breast tissue samples for the expression of QSOX1 mRNAs, significant correlation between relative transcript level and clinical grade malignant breast tumors
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egg white
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endometrial cells. Enzyme level increases during a serum depletion-induced quiescence, decreases when cells enter the g1 phase after serum stimulation, and is restored during the S and G2/M phases
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throughout the rostrocaudal extent of the brain
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immunohistochemic enzyme localization study in hair follicles and keratine structures in the human hair, overview
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high expression in neurons producing disulfide-bounded neuropeptides
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secretion of enzyme
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immunohistochemical expression of the protein quiescin sulfhydryl oxidase 1 (QSOX1) in samples obtained from untreated neuroblastomas with the patients' clinical and pathological prognostic factors and clinical course. The immunoexpression of QSOX1 correlates with the type of tumor stroma and is higher in Schwannian stroma-rich tumors. Statistically significant correlation between QSOX1 expression and well-differentiated neuroblastomas
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several cell lines
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secretory tissue
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fetal and newborn serum
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small amounts
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epithelial cells
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detailed tissue distribution analysis in brain, overview
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highest mRNA contents in cerebellum and diencephalons
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highest enzyme expression in reticular structures, such as the basal forebrain, reticular thalamic nucleus, and reticular nuclei of the brainstem
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glandular epithelial cells
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specific expression in glandular and luminal epithelial cells
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high activity
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high content
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endometrial glandular
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secretory, endometrial
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high expression level of QSOX1
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embroynic fibroblast
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small amounts
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during late embryogenesis
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during late embryogenesis
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cortex
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small amounts
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cortex
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small amounts
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small amounts
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especially in neurons throughout the rostrocaudal extent of the brain as well as in the spinal cord, in olfactory bulbs, isocortex, hippocampus, basal telencephalon, several thalamic and hypothalamic nuclei, cerebellum, and brainstem nuclei
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throughout the rostrocaudal extent of the brain
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small amounts
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fluid, high activity
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high content
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prevalent labelling in the granular, transitional and lowermost part of the stratum corneous layer
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prevalent labelling in the granular, transitional and lowermost part of the stratum corneous layer
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prevalent labelling in the granular, transitional and lowermost part of the stratum corneous layer
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prevalent labelling in the granular, transitional and lowermost part of the stratum corneous layer
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epithelium
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small amounts
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additional information
recombinant baculovirus in Spodoptera frugiperda SF9 insect cells
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additional information
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recombinant baculovirus in Spodoptera frugiperda SF9 insect cells
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additional information
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wide tissue distribution
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additional information
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enzyme is expressed in a large number of different cell types and tissues
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additional information
tissue distribution of enzyme expression
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additional information
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tissue distribution of enzyme expression
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additional information
tissue expression and distribution, high enzyme concentration in cell types associated with heavy secretory loads
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additional information
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tissue expression and distribution, high enzyme concentration in cell types associated with heavy secretory loads
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additional information
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not expressed in asexual erythrocytic stages
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additional information
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not expressed in asexual erythrocytic stages
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additional information
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detailed analysis of cellular and subcellular enzyme localization, overview
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additional information
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in-situ detection of enzyme expression in pituitary gland
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additional information
tissue expression and distribution
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additional information
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enzyme is expressed in a large number of different cell types and tissues
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