1.14.20.3: (5R)-carbapenem-3-carboxylate synthase
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For detailed information about (5R)-carbapenem-3-carboxylate synthase, go to the full flat file.
Reaction
Synonyms
carbapenem synthase, CarC
ECTree
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Systematic Name
Systematic Name on EC 1.14.20.3 - (5R)-carbapenem-3-carboxylate synthase
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(3S,5S)-carbapenam-3-carboxylate,2-oxoglutarate:oxygen oxidoreductase (dehydrating)
Requires Fe2+. The enzyme is involved in the biosynthesis of the carbapenem beta-lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum. It catalyses a stereoinversion at C-5 and introduces a double bond between C-2 and C-3.