Sequence of HMDH_PYRHO
EC Number:1.1.1.34
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
hydroxymethylglutaryl-CoA reductase (NADPH)
O59469
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
413
44554
Reaction
(R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+
Other sequences found for EC No. 1.1.1.34
General information:
Sequence
0 MGGGNLNIEE IIEKVANGEI KFYQVEKYVN GDKRLATEIR RKALEKRLGI KLHHIGYYSI
60 DPNELIGRNI ENMIGVVQIP MGVAGPLKIN GEYAKGEFYI PLATTEGALV ASVNRGCSAL
120 TEAGGVVTTL IDDKMTRAPL IRCPNARRAR EVAKWVEENL DYLQEKAVSK VTRHGKLRGV
180 KPFIVGNNLY LRFEFETGDA MGMNMVTIAS EEIMKVIEEE FPDVRYLALS GNLCVDKKPN
240 AVNFILGRGK TVIAEAVVPR KIVEKKLKTT PELIAEVNYF KNLVGSAQAG SYGFNAHFAN
300 IVGAIFLATG QDEAQITEGA HGITIAEVTP DGDLYISITM PSLEIGTVGG GTRVPSQREA
360 LEIMGVAGGG DPPGINAKKF AEIVAGAVLA GELSLLAAIA AKHLARAHKM LGR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
43819
Kawarabayasi Y.,Sawada M.,Horikawa H.,Haikawa Y.,Hino Y.,Yamamoto S.,Sekine M.,Baba S.,Kosugi H.,Hosoyama A.,Nagai Y.,Sakai M.,Ogura K.,Otsuka R.,Nakazawa H.,Takamiya M.,Ohfuku Y.,Funahashi T.,Tanaka T.,Kudoh Y.,Yamazaki J.,Kushida N.,Oguchi A.,Aoki K.,Yoshizawa T.,Nakamura Y.,Robb F.T.,Horikoshi K.,Masuchi Y.,Shizuya H.,Kikuchi H.
Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.
DNA Res.
5
55-76
1998
