Sequence of EGLN3_RAT
EC Number:1.14.11.29
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-(4R)-4-hydroxy-L-proline + succinate + CO2
Other sequences found for EC No. 1.14.11.29
General information:
Sequence
0 MPLGHIMRLD LEKIALEYIV PCLHEVGFCY LDNFLGEVVG DCVLERVKQL HYNGALRDGQ
60 LAGPRAGVSK RHLRGDQITW IGGNEEGCEA INFLLSLIDR LVLYCGSRLG KYYVKERSKA
120 MVACYPGNGT GYVRHVDNPN GDGRCITCIY YLNKNWDAKL HGGVLRIFPE GKSFVADVEP
180 IFDRLLFSWS DRRNPHEVQP SYATRYAMTV WYFDAEERAE AKKKFRNLTR KTESALAKD
Download this sequence
in fasta formatDownload all sequences for 1.14.11.29
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
29486
Wax S.D.,Rosenfield C.L.,Taubman M.B.
Identification of a novel growth factor-responsive gene in vascular smooth muscle cells.
J. Biol. Chem.
269
13041-13047
1994
29487
Lipscomb E.A.,Sarmiere P.D.,Crowder R.J.,Freeman R.S.
Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons.
J. Neurochem.
73
429-432
1999
29488
Epstein A.C.R.,Gleadle J.M.,McNeill L.A.,Hewitson K.S.,O'Rourke J.,Mole D.R.,Mukherji M.,Metzen E.,Wilson M.I.,Dhanda A.,Tian Y.M.,Masson N.,Hamilton D.L.,Jaakkola P.,Barstead R.,Hodgkin J.,Maxwell P.H.,Pugh C.W.,Schofield C.J.,Ratcliffe P.J.
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.
Cell
107
43-54
2001
29489
Lipscomb E.A.,Sarmiere P.D.,Freeman R.S.
SM-20 is a novel mitochondrial protein that causes caspase-dependent cell death in nerve growth factor-dependent neurons.
J. Biol. Chem.
276
5085-5092
2001
29490
Menzies K.,Liu B.,Kim W.J.,Moschella M.C.,Taubman M.B.
Regulation of the SM-20 prolyl hydroxylase gene in smooth muscle cells.
Biochem. Biophys. Res. Commun.
317
801-810
2004
29491
Hopfer U.,Hopfer H.,Jablonski K.,Stahl R.A.K.,Wolf G.
The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3).
J. Biol. Chem.
281
8645-8655
2006
29492
Willam C.,Maxwell P.H.,Nichols L.,Lygate C.,Tian Y.M.,Bernhardt W.,Wiesener M.,Ratcliffe P.J.,Eckardt K.U.,Pugh C.W.
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
J. Mol. Cell. Cardiol.
41
68-77
2006
29493
Liu Y.,Huo Z.,Yan B.,Lin X.,Zhou Z.N.,Liang X.,Zhu W.,Liang D.,Li L.,Liu Y.,Zhao H.,Sun Y.,Chen Y.H.
Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells.
Biochem. Biophys. Res. Commun.
401
231-237
2010
