Sequence of EGLN2_RAT
EC Number:1.14.11.29
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
hypoxia-inducible factor-L-proline + 2-oxoglutarate + O2 = hypoxia-inducible factor-(4R)-4-hydroxy-L-proline + succinate + CO2
Other sequences found for EC No. 1.14.11.29
General information:
Sequence
show sequence in normal format
>Q6AYU4|hypoxia-inducible factor-proline dioxygenase|EC 1.14.11.29|Rattus norvegicus|Swiss-Prot
MDSPCQPQALNQALPQLPGSVSESLEPSRARMGVESYLPCPLLPSYHRSGASGEASAGNG
TPRTTATATTTTASPLREGFGGQDGGELWPLQSEGAAALVTKECQRLAAQGARPEAPKRK
WAKDGGDAPSPSKRPWARQENQEAKGESGVGCDSGGGSSNSTTHSSGEASSRLREEAQPS
APERLALDYIVPCMRYYGICVKDNFLGAVLGGRVLAEVEALKWGGRLRDGQLVSQRAIPP
RSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGNYVINGRTKAMVACYPGNGL
GYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWS
DRRNPHEVKPAYATRYAITVWYFDAKERAAARDKYQLASGQKGVQVPVSQPATPT
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
29447
Cobb R.R.,McClary J.,Manzana W.,Finster S.,Larsen B.,Blasko E.,Pearson J.,Biancalana S.,Kauser K.,Bringmann P.,Light D.R.,Schirm S.
Cloning and characterization of the rat HIF-1 alpha prolyl-4-hydroxylase-1 gene.
Protein Expr. Purif.
42
295-304
2005
29449
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
29450
Willam C.,Maxwell P.H.,Nichols L.,Lygate C.,Tian Y.M.,Bernhardt W.,Wiesener M.,Ratcliffe P.J.,Eckardt K.U.,Pugh C.W.
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
J. Mol. Cell. Cardiol.
41
68-77
2006
