Sequence of TRDMT_MOUSE
EC Number:2.1.1.204
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
S-adenosyl-L-methionine + cytosine38 in tRNA = S-adenosyl-L-homocysteine + 5-methylcytosine38 in tRNA
Other sequences found for EC No. 2.1.1.204
General information:
Sequence
0 MEPLRVLELY SGIGGMHHAL RESHIPAHVV AAIDVNTVAN EVYKHNFPHT HLLSKTIEGI
60 SLEDFDKLSF NMILMSPPCQ PFTRIGLQGD MTDPRTTSFL YILDILPRLQ KLPKYILLEN
120 VKGFEVSSTR GLLIQTIEAC GFQYQEFLLS PSSLGIPNSR LRYFLIAKLQ SEPFPFQAPG
180 QILMEFPKIV TVEPQKYAVV EESQPRVQRT GPRICAESSS TQSSGKDTIL FKLETVEERD
240 RKHQQDSDLS VQMLKDFLED GDTDEYLLPP KLLLRYALLL DIVKPTSRRS MCFTKGYGSY
300 IEGTGSVLQA AEDAQIENIY KSLPDLPPEE KIAKLSMLKL RYFTPKEIAN LQGFPPEFGF
360 PEKTTVKQRY RLLGNSLNVH VVAKLLTVLC EGFGNASESC HKMPLILDSN SKILS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
243421
Yoder J.A.,Bestor T.H.
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast.
Hum. Mol. Genet.
7
279-284
1998
243422
Okano M.,Xie S.,Li E.
Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells.
Nucleic Acids Res.
26
2536-2540
1998
243423
Goll M.G.,Kirpekar F.,Maggert K.A.,Yoder J.A.,Hsieh C.L.,Zhang X.,Golic K.G.,Jacobsen S.E.,Bestor T.H.
Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2.
Science
311
395-398
2006
243424
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
243425
Tuorto F.,Liebers R.,Musch T.,Schaefer M.,Hofmann S.,Kellner S.,Frye M.,Helm M.,Stoecklin G.,Lyko F.
RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis.
Nat. Struct. Mol. Biol.
19
900-905
2012
