EC Number |
Protein Variants |
Reference |
---|
3.4.24.55 | F198A |
enzyme remains functional |
667533 |
3.4.24.55 | H193A |
enzyme remains functional |
667533 |
3.4.24.55 | K197A |
enzyme remains functional |
667533 |
3.4.24.55 | N317A/R318A/S319A |
enzyme remains functional |
667533 |
3.4.24.55 | S117A |
enzyme remains functional |
667533 |
3.4.24.55 | T127A |
enzyme remains functional |
667533 |
3.4.24.55 | T322A/L323A |
enzyme remains functional |
667533 |
3.4.24.55 | more |
heterologous expression of enzyme in yeast, enzyme functionally substitutes for yeast Ax11p and Ste23p in pheromone production. Independent heterologous expression of N-terminal domain with amino acids 1-515 or C-terminal domain with amino acids 516-962 does not promote yeast mating. Co-expression of both domains restores yeast mating |
667533 |
3.4.24.55 | D79A |
no effect on function |
667533 |
3.4.24.55 | E91A |
no proteolytic activity |
667533 |