EC Number   |
Protein Variants |
Reference |
|---|
   3.4.23.B4 | D30N |
- |
647828 |
| 3.4.23.B4 | D30N |
inactive mutant |
-, 668799 |
| 3.4.23.B4 | D30N |
inactive mutant enzyme |
647828 |
| 3.4.23.B4 | D30N |
mutant enzyme can bind substrate but is inactive |
647835 |
| 3.4.23.B4 | D30N |
site-directed mutagenesis, the mutant shows highly reduced activity compared to the wild-type enzyme |
-, 670098 |
| 3.4.23.B4 | G5I/N55T |
only 25% loss of activity after 16 h at pH 7.0, 37°C, in 0.2 M NaCl, compared to 65% loss of the wild-type enzyme |
647835 |
| 3.4.23.B4 | G5I/N55T/C84K |
autoproteolysis-resistant mutant, no significant change in Km or turnover number values between the mutant enzyme and the wild-type enzyme |
647829 |
| 3.4.23.B4 | I35D |
mutant enzyme shows no activity against either FIV or HIV substrates |
647836 |
| 3.4.23.B4 | I35D |
site-directed mutagenesis, the mutant shows about 30% reduced activity compared to the wild-type enzyme |
-, 670098 |
| 3.4.23.B4 | I35D/I37V |
mutant enzyme shows no activity against either FIV or HIV substrates |
647836 |
