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EC Number
Protein Variants
Commentary
Reference
3.2.2.19
D77/78N
mutant does not hydrolyze poly(ADP-ribose)
682516
3.2.2.19
E238/239Q
mutant hydrolyzes O-acetyl-ADP-ribose at rates similar to that of the wild-type
682516
3.2.2.19
E261/262Q
mutant hydrolyzes O-acetyl-ADP-ribose at rates similar to that of the wild-type
682516
3.2.2.19
E756D
the mutation completely abolishes catalytic activity
732219
3.2.2.19
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The activity is abolished upon mutation of even a single Mg2+ coordinating residue
750260
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