EC Number |
Protein Variants |
Reference |
---|
2.8.2.9 | C232S |
mutant is catalytically active |
644835 |
2.8.2.9 | C66S |
mutant is catalytically active, can not be activated by glutathione disulfide |
644835 |
2.8.2.9 | F138A |
25fold increase in KM-value for (R)-(-)-tetrahydro-1-naphthol. Unlike the wild-type enzyme the mutant enzyme is also active with (S)-(+)-1,2,3,4-tetrahydro-1-naphthol |
661579 |
2.8.2.9 | F77A |
83.3fold increase in KM-value for (R)-(-)-tetrahydro-1-naphthol,unlike the wild-type enzyme the mutant enzyme is also active with (S)-(+)-1,2,3,4-tetrahydro-1-naphthol |
661579 |
2.8.2.9 | G208R |
same pattern of specific activities as wild-type enzyme |
644826 |
2.8.2.9 | H104A |
no enzymatic activity |
644828 |
2.8.2.9 | Y236A |
116.7fold increase in KM-value for (R)-(-)-tetrahydro-1-naphthol |
661579 |