EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.1.1.98 | Adenoma |
34079124 |
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 1 3 1 |
3.1.1.98 | Alzheimer Disease |
33033363 |
Caffeine inhibits Notum activity by binding at the catalytic pocket. |
causal interaction therapeutic application unassigned |
3 4 0 |
3.1.1.98 | Alzheimer Disease |
34292747 |
Structural Insights into Notum Covalent Inhibition. |
causal interaction therapeutic application unassigned |
4 4 0 |
3.1.1.98 | Carcinoma |
34402722 |
Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 3 |
3.1.1.98 | Carcinoma, Hepatocellular |
18429952 |
Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF. |
diagnostic usage ongoing research unassigned |
3 4 0 |
3.1.1.98 | Colonic Neoplasms |
34402722 |
Notum palmitoleoyl-protein carboxylesterase regulates Fas cell surface death receptor-mediated apoptosis via the Wnt signaling pathway in colon adenocarcinoma. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 3 |
3.1.1.98 | Colorectal Neoplasms |
26517809 |
Novel insights into Notum and glypicans regulation in colorectal cancer. |
ongoing research unassigned |
1 0 |
3.1.1.98 | Colorectal Neoplasms |
30343282 |
NOTUM Is Involved in the Progression of Colorectal Cancer. |
causal interaction diagnostic usage unassigned |
4 3 0 |
3.1.1.98 | Colorectal Neoplasms |
34079124 |
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 1 3 1 |
3.1.1.98 | Dentin Dysplasia |
26926082 |
Dentin Dysplasia in Notum Knockout Mice. |
ongoing research therapeutic application unassigned |
4 2 0 |