EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.4.1.80 | Breast Neoplasms |
29549423 |
UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells. |
causal interaction
ongoing research
therapeutic application
unassigned |
1
4
1
0 |
| 2.4.1.80 | ceramide glucosyltransferase deficiency |
29417556 |
Identification of a novel lethal form of autosomal recessive ichthyosis caused by UDP-glucose ceramide glucosyltransferase deficiency. |
causal interaction
unassigned |
4
0 |
| 2.4.1.80 | Gaucher Disease |
14609352 |
Miglustat. |
causal interaction
unassigned |
3
0 |
| 2.4.1.80 | Gaucher Disease |
23628459 |
Glucosylceramide modulates endolysosomal pH in Gaucher disease. |
causal interaction
therapeutic application
unassigned |
4
4
0 |
| 2.4.1.80 | Gaucher Disease |
26724485 |
Glucosylated cholesterol in mammalian cells and tissues: formation and degradation by multiple cellular ?-glucosidases. |
ongoing research
unassigned |
2
0 |
| 2.4.1.80 | Gaucher Disease |
32461019 |
A novel method for preparing Eligulstat through chiral resolution. |
causal interaction
therapeutic application
unassigned |
3
4
0 |
| 2.4.1.80 | Gaucher Disease |
32705968 |
The sirtuin inhibitor cambinol reduces intracellular glucosylceramide with ceramide accumulation by inhibiting glucosylceramide synthase. |
causal interaction
unassigned |
3
0 |
| 2.4.1.80 | Ichthyosis |
29417556 |
Identification of a novel lethal form of autosomal recessive ichthyosis caused by UDP-glucose ceramide glucosyltransferase deficiency. |
causal interaction
unassigned |
4
0 |
| 2.4.1.80 | Infections |
11254758 |
Regulation of sphingolipid and glycosphingolipid metabolism in extrahepatic tissues by endotoxin. |
ongoing research
unassigned |
4
0 |
| 2.4.1.80 | Lysosomal Storage Diseases |
24115322 |
Glucosylceramide mimics: highly potent GCase inhibitors and selective pharmacological chaperones for mutations associated with types?1 and 2 Gaucher disease. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
