EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
14708602 |
Truncation of CGI-58 protein causes malformation of lamellar granules resulting in ichthyosis in Dorfman-Chanarin syndrome. |
causal interaction unassigned |
4 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
19187773 |
Molecular mechanisms of hepatic steatosis and insulin resistance in the AGPAT2-deficient mouse model of congenital generalized lipodystrophy. |
causal interaction unassigned |
4 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
19494770 |
Inherited lipodystrophies and hypertriglyceridemia. |
causal interaction therapeutic application unassigned |
4 1 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
21051554 |
Pathology of Congenital Generalized Lipodystrophy in Agpat2 -/-Mice. |
causal interaction unassigned |
2 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
25482557 |
Loss of abhd5 promotes colorectal tumor development and progression by inducing aerobic glycolysis and epithelial-mesenchymal transition. |
causal interaction ongoing research unassigned |
3 2 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
26417690 |
AGPAT2 deficiency impairs adipogenic differentiation in primary cultured preadipocytes in a non-autophagy or apoptosis dependent mechanism. |
causal interaction unassigned |
3 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
27559856 |
ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. |
causal interaction ongoing research therapeutic application unassigned |
3 2 1 0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
30842415 |
ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield. |
unassigned |
0 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
31439546 |
Macrophage ABHD5 suppresses NF-?B-dependent matrix metalloproteinase expression and cancer metastasis. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 4 1 |
2.3.1.51 | 1-acylglycerol-3-phosphate o-acyltransferase deficiency |
32810486 |
Absence of AGPAT2 impairs brown adipogenesis, increases IFN stimulated gene expression and alters mitochondrial morphology. |
causal interaction diagnostic usage ongoing research unassigned |
2 3 3 0 |