EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   2.3.1.199 | Acanthosis Nigricans |
30487246 |
De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy. |
causal interaction
unassigned |
2
0 |
| 2.3.1.199 | Adrenoleukodystrophy |
20166112 |
The role of ELOVL1 in very long-chain fatty acid homeostasis and X-linked adrenoleukodystrophy. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
1
4
0 |
| 2.3.1.199 | Adrenoleukodystrophy |
22911730 |
Bezafibrate for x-linked adrenoleukodystrophy. |
causal interaction
therapeutic application
unassigned |
2
4
0 |
| 2.3.1.199 | Adrenoleukodystrophy |
25499606 |
Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
4
1 |
| 2.3.1.199 | Breast Neoplasms |
21415164 |
Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression. |
unassigned |
0 |
| 2.3.1.199 | Breast Neoplasms |
27788154 |
Estrogen Enhances the Expression of the Polyunsaturated Fatty Acid Elongase Elovl2 via ER? in Breast Cancer Cells. |
ongoing research
unassigned |
3
0 |
| 2.3.1.199 | Corneal Opacity |
29401594 |
Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice. |
unassigned |
0 |
| 2.3.1.199 | Deafness |
30487246 |
De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy. |
causal interaction
unassigned |
2
0 |
| 2.3.1.199 | Deafness |
32123819 |
Reduced chain length in myelin sphingolipids and poorer motor coordination in mice deficient in the fatty acid elongase Elovl1. |
causal interaction
ongoing research
therapeutic application
unassigned |
3
4
1
0 |
| 2.3.1.199 | Demyelinating Diseases |
20035504 |
Dicer ablation in oligodendrocytes provokes neuronal impairment in mice. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
