EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.14.99.60 | 3-demethoxyubiquinol 3-hydroxylase deficiency |
18343482 |
Clk-1 deficiency induces apoptosis associated with mitochondrial dysfunction in mouse embryos. |
causal interaction
unassigned |
4
0 |
| 1.14.99.60 | Carcinoma, Hepatocellular |
17901468 |
Evolutionary conservation of drug action on lipoprotein metabolism-related targets. |
causal interaction
unassigned |
2
0 |
| 1.14.99.60 | Infertility |
11136229 |
A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants. |
ongoing research
unassigned |
2
0 |
| 1.14.99.60 | Infertility |
12324451 |
Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria. |
therapeutic application
unassigned |
1
0 |
| 1.14.99.60 | Neurodegenerative Diseases |
18927074 |
The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1. |
therapeutic application
unassigned |
1
0 |
| 1.14.99.60 | Starvation |
10335847 |
A cytosolic catalase is needed to extend adult lifespan in C. elegans daf-C and clk-1 mutants. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
