EC Number   |
Disease |
PubMed ID  |
Title of Publication |
Category |
Confidence Level |
|---|
   3.4.22.53 | Cataract |
1440613 |
Comparison of cell-permeable calpain inhibitors and E64 in reduction of cataract in cultured rat lenses. |
causal interaction
ongoing research
therapeutic application
unassigned |
2
2
4
0 |
| 3.4.22.53 | Infections |
1527057 |
Expression of calpain II gene in human hematopoietic system cells infected with human T-cell leukemia virus type I. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.22.53 | Leukemia, T-Cell |
1527057 |
Expression of calpain II gene in human hematopoietic system cells infected with human T-cell leukemia virus type I. |
causal interaction
diagnostic usage
ongoing research
unassigned |
4
3
4
0 |
| 3.4.22.53 | Cataract |
1608594 |
Hydration and elevated calcium alone do not produce xylose nuclear cataract: role of proteolysis by calpain. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
1
3
1 |
| 3.4.22.53 | Cataract |
1627659 |
Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract. |
causal interaction
unassigned |
3
0 |
| 3.4.22.53 | Alzheimer Disease |
1718565 |
Presence of calpain II immunoreactivity in senile plaques in Alzheimer's disease. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
1
3
1 |
| 3.4.22.53 | Cataract |
1848210 |
Amelioration of cataracts and proteolysis in cultured lenses by cysteine protease inhibitor E64. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
2
4
0 |
| 3.4.22.53 | Alzheimer Disease |
2072120 |
Comparison of Ca(2+)-activated proteinase enzyme and endogenous inhibitor activity in brain tissue from normal and Alzheimer's disease cases. |
diagnostic usage
ongoing research
unassigned |
3
4
0 |
| 3.4.22.53 | Leukemia-Lymphoma, Adult T-Cell |
2203051 |
Gene expression for calpain isozymes in human hematopoietic system cells. |
diagnostic usage
ongoing research
unassigned |
1
1
0 |
| 3.4.22.53 | Cataract |
2209751 |
Calpain II in two in vivo models of sugar cataract. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
4
2
1
0 |
