EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.1.1.239 | Prostatic Neoplasms |
27486833 |
Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
3
1
4 |
| 1.1.1.239 | Prostatic Neoplasms |
28359237 |
Influence of Aldo-keto reductase 1C3 in prostate cancer -a mini review. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
2
1
0 |
| 1.1.1.239 | Prostatic Neoplasms |
28881288 |
Hydroxytriazole derivatives as potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors discovered by bioisosteric scaffold hopping approach. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 1.1.1.239 | Prostatic Neoplasms |
29602039 |
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
2
1
0 |
| 1.1.1.239 | Prostatic Neoplasms |
29891491 |
AKR1C3 Inhibitor KV-37 Exhibits Antineoplastic Effects and Potentiates Enzalutamide in Combination Therapy in Prostate Adenocarcinoma Cells. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
2
4
4 |
| 1.1.1.239 | Prostatic Neoplasms |
29920533 |
Influence of lifestyle and genetic variants in the aldo-keto reductase 1C3 rs12529 polymorphism in high-risk prostate cancer detection variability assessed between US and New Zealand cohorts. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
4
1
0 |
| 1.1.1.239 | Prostatic Neoplasms |
29936123 |
11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): Implications for castration resistant prostate cancer. |
causal interaction
diagnostic usage
therapeutic application
unassigned |
3
2
2
0 |
| 1.1.1.239 | Prostatic Neoplasms |
30108986 |
Evaluation of A-ring fused pyridine d-modified androstane derivatives for antiproliferative and aldo-keto reductase 1C3 inhibitory activity. |
causal interaction
unassigned |
1
0 |
| 1.1.1.239 | Prostatic Neoplasms |
31125365 |
Interaction between leukocyte aldo-keto reductase 1C3 activity, genotypes, biological, lifestyle and clinical features in a prostate cancer cohort from New Zealand. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
1
4
3
1 |
| 1.1.1.239 | Tics |
10733348 |
Regulation of thyroid hormones on the production of testosterone in rats. |
causal interaction
therapeutic application
unassigned |
3
1
0 |
