EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.22.53 | Cataract |
1627659 |
Calpain II induced insolubilization of lens beta-crystallin polypeptides may induce cataract. |
causal interaction unassigned |
3 0 |
3.4.22.53 | Cataract |
2536646 |
Calpain II in human lens. |
causal interaction unassigned |
4 0 |
3.4.22.53 | Cataract |
3011481 |
Purification of calpain II from rat lens and determination of endogenous substrates. |
causal interaction unassigned |
4 0 |
3.4.22.53 | Cataract |
7821381 |
Calpains in lens epithelium from patients with cataract. |
causal interaction unassigned |
1 0 |
3.4.22.53 | Cataract |
8125740 |
Cataract and the acceleration of calpain-induced beta-crystallin insolubilization occurring during normal maturation of rat lens. |
causal interaction ongoing research unassigned |
3 2 0 |
3.4.22.53 | Cataract |
8405363 |
Beta-crystallins insolubilized by calpain II in vitro contain cleavage sites similar to beta-crystallins insolubilized during cataract. |
causal interaction unassigned |
3 0 |
3.4.22.53 | Cataract |
9733588 |
Protein for Lp82 calpain is expressed and enzymatically active in young rat lens. |
causal interaction unassigned |
1 0 |
3.4.22.53 | Cataract |
10694893 |
Lp85 calpain is an enzymatically active rodent-specific isozyme of lens Lp82. |
causal interaction unassigned |
3 0 |
3.4.22.53 | Cataract |
10798663 |
Contribution of calpain Lp82-induced proteolysis to experimental cataractogenesis in mice. |
causal interaction unassigned |
2 0 |
3.4.22.53 | Cataract |
10964662 |
Evidence for apoptosis in the selenite rat model of cataract. |
causal interaction diagnostic usage unassigned |
1 3 0 |