EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   7.4.2.5 | -999 |
- |
beta-Ala-Lys |
IC50 value range between 0.1 and 1 mM for wild-type and E20-mutants, and increase to above 10 mM for mutant E388Q, pH not specified in the publication, temperature not specified in the publication |
720986 |
| 7.4.2.5 | -999 |
- |
Gly-Lys |
IC50 value range between 0.1 and 1 mM for wild-type and E20-mutants, and increase to about 2 mM for mutant E388Q, pH not specified in the publication, temperature not specified in the publication |
720986 |
| 7.4.2.5 | 0.0005 |
- |
Rose bengal |
truncated SecA without the C-terminal regulatory domain, pH 7.6, 40°C |
719303 |
| 7.4.2.5 | 0.002 |
- |
2,2'-(alpha,alpha'-xylene)bis(sulfanediyl)bis-(6-(4-bromophenyl)-5-cyano-4-oxopyrimidine) |
EcN68, the N-terminal fragment of SecA without the C-terminal regulatory domain, pH 7.6, 40°C |
719076 |
| 7.4.2.5 | 0.002 |
- |
2,2'-(alpha,alpha'-xylene)bis(sulfanediyl)bis-(6-(biphenyl-4-yl)-5-cyano-4-oxopyrimidine) |
EcN68, the N-terminal fragment of SecA without the C-terminal regulatory domain, pH 7.6, 40°C |
719076 |
| 7.4.2.5 | 0.002 |
- |
erythrosin B |
truncated SecA without the C-terminal regulatory domain, 40°C, pH 7.6 |
719303 |
| 7.4.2.5 | 0.0022 |
- |
2-((4-azidobenzyl)thio)-6-oxo-4-(4-phenoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile |
37°C, pH not specified in the publication |
733509 |
| 7.4.2.5 | 0.0024 |
- |
2-((4-azidobenzyl)thio)-4-(4-(benzyloxy)phenyl)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile |
37°C, pH not specified in the publication |
733509 |
| 7.4.2.5 | 0.016 |
- |
orthovanadate |
IC50: 0.016 mM, competitive |
667495 |
| 7.4.2.5 | 0.02 |
- |
2,2'-(alpha,alpha'-xylene)bis(sulfanediyl)bis-(6-(4-bromophenyl)-5-cyano-4-oxopyrimidine) |
recombinant SecA, pH 7.6, 40°C |
719076 |
