EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
3.4.23.38 | 0.0017 |
- |
(1S,2aR,3aR,3bS,4R,9aR,11aS)-2-(((1-(2-cyanophenyl)-1H-1,2,3-triazol-4-yl)methoxy)imino)-1-(furan-3-yl)-3b,6,6,9a,11a-pentamethyl-7-oxo-1,2,2a,3b,4,5,5a,6,7,9a,9b,10,11,11a-tetradecahydronaphtho(1,2':6,7)indeno(1,7a-b)oxiren-4-yl acetate |
pH and temperature not specified in the publication |
754205 |
3.4.23.38 | 0.0021 |
- |
(1S,2S,3S,4R)-3-(4-hexylphenylsulfonyl)-N-((2'-methoxybiphenyl-3-yl)methyl)-7-azabicyclo[2.2.1]heptan-2-amine |
- |
677552 |
3.4.23.38 | 0.00037 |
- |
(1S,2S,3S,4R)-3-(4-hexylphenylsulfonyl)-N-(naphthalen-2-ylmethyl)-7-azabicyclo[2.2.1]heptan-2-amine |
- |
677552 |
3.4.23.38 | 0.00067 |
- |
(1S,2S,3S,4R)-N-(3-bromobenzyl)-3-(4-hexylphenylsulfonyl)-7-azabicyclo[2.2.1]heptan-2-amine |
- |
677552 |
3.4.23.38 | 0.000727 |
- |
(3S,4S)-N-butyl-3-hydroxy-6-methyl-4-((2S,3S)-3-methyl-2-(2-(naphthalen-2-yloxy)acetamido)pentanamido)heptanamide |
- |
681296 |
3.4.23.38 | 0.000017 |
- |
(S)-propyl 6-(tert-butoxycarbonylamino)-2-((S)-2-(4-(4-((2S,3S)-1-((3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-ylamino)-3-methyl-1-oxopentan-2-ylcarbamoyl)phenoxy)benzamido)-4-methylpentanamido)hexanoate |
not cytotoxic against human fibroblasts at 0.100 mM and are highly selective for plasmepsins vs human cathepsin D |
681296 |
3.4.23.38 | 0.000011 |
- |
(S)-propyl 6-amino-2-((S)-2-(4-(4-((2S,3S)-1-((3S,4S)-1-(butylamino)-3-hydroxy-6-methyl-1-oxoheptan-4-ylamino)-3-methyl-1-oxopentan-2-ylcarbamoyl)phenoxy)benzamido)-4-methylpentanamido)hexanoate |
- |
681296 |
3.4.23.38 | 0.022 |
- |
1-[2-hydroxy-3-(1,2,3,4,5,6,7,8-octahydrophenanthren-9-yloxy)propyl]-4-(3-methoxyphenyl)piperazin-1-ium |
pH 5.0, temperature not specified in the publication |
708121 |
3.4.23.38 | 0.000629 |
- |
2,3-difluoro-4-methyl-N-[4-([[1-(3-methylbutyl)piperidin-4-yl][(4-pentylphenyl)carbonyl]amino]methyl)phenyl]benzamide |
- |
679228 |
3.4.23.38 | 0.00093 |
- |
3'-(((1S,2S,3S,4R)-3-(4-hexylphenylsulfonyl)-7-azabicyclo[2.2.1]heptan-2-ylamino)methyl)biphenyl-2-ol |
- |
677552 |