EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   2.7.7.48 | more |
the central polymerase domain (PD) shows nucleotide binding properties, but neither the N-terminal domain (NTD) nor the C-terminal domain (CTD). Isolated PD does not exhibit RdRp activity but this activity can be reconstituted when all three domains are included in the reaction mixture. Molecular dynamics simulation suggests that the isolated PD has increased internal motions in comparison to when it is associated with the NTD and CTD. The motions of the separated PD may lead to the formation of a less accessible RNA template-binding channel and, thus, impair RdRp activity |
Antheraea mylitta cypovirus 4 |
? |
- |
? |
| 2.7.7.48 | nucleoside triphosphate + RNAn |
- |
Antheraea mylitta cypovirus 4 |
diphosphate + RNAn+1 |
- |
? |
| 2.7.7.48 | more |
introns called mirtrons and sirtrons might serve as the single-stranded RNA precursors for the generation of microRNA and small interfering RNA (siRNA), respectively, through an RDR (RNA-dependent RNA polymerase)-dependent pathway. sRNA high-throughput sequencing in wild-type and RDR-deficient mutant plants, overview |
Arabidopsis thaliana |
? |
- |
? |
| 2.7.7.48 | nucleoside triphosphate + RNAn |
- |
Arabidopsis thaliana |
diphosphate + RNAn+1 |
- |
? |
| 2.7.7.48 | more |
introns called mirtrons and sirtrons might serve as the single-stranded RNA precursors for the generation of microRNA and small interfering RNA (siRNA), respectively, through an RDR (RNA-dependent RNA polymerase)-dependent pathway. sRNA high-throughput sequencing in wild-type and RDR-deficient mutant plants, overview |
Arabidopsis thaliana Col-0 |
? |
- |
? |
| 2.7.7.48 | nucleoside triphosphate + RNAn |
- |
bamboo mosaic virus |
diphosphate + RNAn+1 |
- |
? |
| 2.7.7.48 | nucleoside triphosphate + RNAn |
the enzyme should be involved in the replication of BaMV |
bamboo mosaic virus |
diphosphate + RNAn+1 |
- |
? |
| 2.7.7.48 | more |
the conservative lysine residue K369 in motif D is a dynamic element whose position inside the polymerase molecule may determine the velocity of the enzymatic reaction |
Birnaviridae |
? |
- |
? |
| 2.7.7.48 | nucleoside triphosphate + RNAn |
full-length negative strand BBV RNAs are synthesized |
black beetle virus |
diphosphate + RNAn+1 |
- |
? |
| 2.7.7.48 | UTP + RNAn |
- |
black beetle virus |
diphosphate + RNAn+1 |
- |
? |
