Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 6 of 6
download as CSV
download all results as CSV
EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296more a conventional 5'-terminal structure of eukaryotic mRNAs consists of a 7-methylguanosine (m7G) moiety linked to the first transcribed nucleotide by a 5' to 5' triphosphate bridge resulting in the structure m7GpppN, which is referred to as cap 0, and most often the first and second transcribed nucleotide carry 2'-O-methyl groups (cap 1 and cap 2 structures, respectively). The cap2 methyltransferase, EC 2.1.1.296 transfers the methyl group to the second nucleotide. In contrast, four nucleotides adjacent to the m7G cap are methylated at the SL RNA 5' end to generate a cap 4 structure: m7G-ppp-N6,N6,2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3,2'-O-methyluridine. The cap 4 structure seems to be restricted to the family Trypanosomatidae Trypanosoma brucei ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296more hMTr2 protein transfers a methyl group from S-adenosylmethionine to the 2'-O-ribose of the second nucleotide of messenger RNA and small nuclear RNA Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296more the enzyme builds the cap 4 structure, usage of an assay with digestion with ribonuclease T2, to monitor the presence of 2'-O-modifications at positions +1 to +4 of the SL sequence Trypanosoma brucei ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296more the recombinant enzyme produces a RNase T2-resistant RNA fragment, cap012, from cap01-RNA, but shows no activity with a purified BAP protein. Only a subset of labeled RNA molecules that has GpppG incorporated during transcription is a substrate for hMTr2. hMTr2 recognizes TMG-capped snRNAs in vitro Homo sapiens ? - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296S-adenosyl-L-methionine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(ribonucleotide)-[mRNA] - Trypanosoma brucei S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)-[mRNA] - ?
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296S-adenosyl-L-methionine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(ribonucleotide)-[mRNA] - Homo sapiens S-adenosyl-L-homocysteine + a 5'-(N7-methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-(2'-O-methyl-ribonucleotide)-[mRNA] - ?
Results 1 - 6 of 6
download as CSV
download all results as CSV