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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 16S rRNA	-	Geobacillus stearothermophilus	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 16S rRNA	-	?
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 16S rRNA	-	Mycobacterium tuberculosis	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 16S rRNA	-	?
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 16S rRNA	-	Streptomyces coelicolor	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 16S rRNA	-	?
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 16S rRNA	-	Mycobacterium tuberculosis H37Rv	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 16S rRNA	-	?
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 30S rRNA	-	Mycolicibacterium smegmatis	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 30S rRNA	-	?
2.1.1.227	S-adenosyl-L-methionine + cytidine1409 in 30S rRNA	-	Mycolicibacterium smegmatis mc(2)155	S-adenosyl-L-homocysteine + 2'-O-methylcytidine1409 in 30S rRNA	-	?
2.1.1.227	more	the 2'-O-methyltransferase TlyA from Mycobacterium tuberculosis methylates both nucleotide C1409 of 16S rRNA and C1920 of 23S rRNA, EC 2.1.1.226	Mycobacterium tuberculosis	?	-	?
2.1.1.227	more	the 2'-O-methyltransferase TlyA from Mycobacterium tuberculosis methylates both nucleotide C1409 of 16S rRNA and C1920 of 23S rRNA, EC 2.1.1.226	Mycobacterium tuberculosis H37Rv	?	-	?
2.1.1.227	more	the bifunctional enzyme exhibits the activities of EC 2.1.1.226 and EC 2.1.1.227	Mycobacterium tuberculosis	?	-	-
2.1.1.227	more	the bifunctional enzyme exhibits the activities of EC 2.1.1.226 and EC 2.1.1.227	Mycobacterium tuberculosis H37Rv	?	-	-

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Release 2023.1 (January 2023)