EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
    1.5.1.27 | 1,2-dehydro-N-methylcoclaurine + NADPH + H+ |
PrDRR reduces 1,2-dehydro-N-methylcoclaurine to N-methylcoclaurine, although the low product yield precludes determination of the enantiomer |
Papaver rhoeas |
N-methylcoclaurine + NADP+ |
- |
? |
| 1.5.1.27 | 1,2-dehydro-N-methylcoclaurine + NADPH + H+ |
PsDRR1 reduces 1,2-dehydro-N-methylcoclaurine to N-methylcoclaurine, although the low product yield precludes determination of the enantiomer |
Papaver somniferum |
N-methylcoclaurine + NADP+ |
- |
? |
| 1.5.1.27 | 1,2-Dehydroreticuline + NADPH |
formation of the precursor of morphinan alkaloids |
Papaver somniferum |
? |
- |
? |
| 1.5.1.27 | 1,2-Dehydroreticuline + NADPH |
the enzyme catalyzes the provision of (R)-reticuline for the formation of morphinian alkaloids that possess also (R)-configuration at the chiral centre |
Papaver somniferum |
? |
- |
? |
| 1.5.1.27 | 1,2-dehydroreticuline + NADPH + H+ |
- |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
? |
| 1.5.1.27 | 1,2-dehydroreticuline + NADPH + H+ |
- |
Papaver bracteatum |
(R)-reticuline + NADP+ |
- |
? |
| 1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
- |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
? |
| 1.5.1.27 | 1,2-dehydroreticulinium + NADPH + H+ |
the enzyme catalyzes a stereospecific reduction of the C=N double bond in 1,2-dehydroreticuline to (R)-reticuline |
Papaver somniferum |
(R)-reticuline + NADP+ |
- |
? |
| 1.5.1.27 | more |
the bifunctional CYP82Y2 fusion enzyme termed reticuline epimerase (PsREPI) is a fusion between a cytochrome P450 (CYP) and an aldo-keto reductase (AKR) catalyzes the S-to-R epimerization of reticuline via 1,2-dehydroreticuline |
Papaver somniferum |
? |
- |
? |
| 1.5.1.27 | more |
enzyme PsREPI also catalyzes the stereochemical inversion of (S)-N-methylcoclaurine |
Papaver somniferum |
? |
- |
? |
