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EC Number
Substrates
Commentary Substrates
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Commentary (Products)
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1.3.1.76
more
large multifunctional protein that catalyzes four diverse reactions, 2 S-adensyl-L-methionine-dependent methylations, NAD+-dependent tetrapyrrole dehydrogenation and metal chelation
Salmonella enterica
?
-
?
1.3.1.76
precorrin-2 + NAD+
-
Salmonella enterica subsp. enterica serovar Typhimurium
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Escherichia coli
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Saccharomyces cerevisiae
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Salmonella enterica
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Priestia megaterium
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Rhizobium etli
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
-
Staphylococcus aureus
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
unlike Met8p and CysG, SirC has no chelatase activity
Priestia megaterium
sirohydrochlorin + NADH + H+
-
?
1.3.1.76
precorrin-2 + NAD+
bifunctional dehydrogenase and ferrochelatase, second of three steps leading to formation of siroheme from uroporphyrinogen III
Saccharomyces cerevisiae
sirohydrochlorin + NADH + H+
-
?
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