EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.2.1.104 | 2-oxobutanoate + CoA + NAD+ |
- |
Pisum sativum |
propanoyl-CoA + CO2 + NADH |
- |
? |
1.2.1.104 | 2-oxobutyrate + CoA + NAD+ |
- |
Brassica oleracea |
propanoyl-CoA + CO2 + NADH + H+ |
- |
r |
1.2.1.104 | 2-oxoisovalerate + CoA + NAD+ |
- |
[Bacillus] caldolyticus |
isobutanoyl-CoA + CO2 + NADH |
- |
? |
1.2.1.104 | acetaldehyde + benzaldehyde |
- |
Pisum sativum |
(R)-phenylacetylcarbinol |
- |
? |
1.2.1.104 | acetaldehyde + benzaldehyde |
- |
Rhodospirillum rubrum |
(R)-phenylacetylcarbinol |
- |
? |
1.2.1.104 | hydroxyethyl thiamine diphosphate + CoA + NAD+ |
- |
Lactococcus lactis subsp. lactis |
? + NADH |
- |
? |
1.2.1.104 | more |
E1 is bound to E2, both components of the pyruvate dehydrogenase multienzyme complex PDC, via the E1-binding B domain of E2, enzyme component organization in the pyruvate dehydrogenase multienzyme complex, regulatory role, overview |
Bos taurus |
? |
- |
? |
1.2.1.104 | more |
pyruvate-supported mitochondrial respiration state 3 |
Rattus norvegicus |
? |
- |
? |
1.2.1.104 | more |
regulation of pyruvate dehydrogenase complex activity and citric acid cycle intermediates during high cardiac power generation, inhibition of fatty acid oxidation has a regulatory function, overview |
Sus scrofa |
? |
- |
? |
1.2.1.104 | more |
in vivo there are 20-30 E1 molecules bound to each core of the mammalian PDC, the small binding domain of E2 in humans binds only to E1 |
Homo sapiens |
? |
- |
? |