EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.2.26 | 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O |
- |
Penicillium chrysogenum |
3 AMP + 3 diphosphate + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine |
- |
? |
6.3.2.26 | 3 ATP + L-2-aminohexanedioate + L-cysteine + L-valine + H2O |
- |
Penicillium chrysogenum Wisconsin 54-1255 |
3 AMP + 3 diphosphate + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine |
- |
? |
6.3.2.26 | more |
ACVSs are multifunctional enzymes that activate amino acids as aminoacyladenylates, forming a mixed anhydride with the a-phosphate group of ATP and releasing pyrophosphate |
Actinomyces sp. |
? |
- |
? |
6.3.2.26 | more |
pure Streptomyces lactamdurans ACVS is able to activate alpha-aminoadipic acid or its lactam 6-oxopiperideine-2-carboxylic acid, a compound that is easily converted to alpha-aminoadipic acid, but is unable to use piperideine-6-carboxylate or pipecolic acid as substrates, enzyme is also able to use L-cystathionine with the same efficiency as L-cysteine |
Actinomyces sp. |
? |
- |
? |
6.3.2.26 | ATP + (R)-4-phosphopantoate + beta-alanine |
the enzyme is involved in coenzyme A biosynthesis in the archaea |
Thermococcus kodakarensis |
AMP + diphosphate + (R)-4'-phosphopantothenate |
- |
? |
6.3.2.26 | ATP + (R)-4-phosphopantoate + beta-alanine |
strict preference for ATP. Among several amine substrates, activity is detected with beta-alanine, but not with gamma-aminobutyrate, glycine nor aspartate |
Thermococcus kodakarensis |
AMP + diphosphate + (R)-4'-phosphopantothenate |
- |
? |
6.3.2.26 | L-2-aminoadipate + allylglycine + L-valine + ATP |
- |
Acremonium chrysogenum |
L-delta-(aminoadipyl)-L-allylglycinyl-D-valine + AMP + diphosphate |
- |
? |
6.3.2.26 | L-2-aminoadipate + allylglycine + L-valine + ATP |
- |
Streptomyces clavuligerus |
L-delta-(aminoadipyl)-L-allylglycinyl-D-valine + AMP + diphosphate |
- |
? |
6.3.2.26 | L-2-aminoadipate + L-cysteine + L-allo-isoleucine + ATP |
- |
Acremonium chrysogenum |
L-delta-(aminoadipyl)-L-cysteinyl-D-allo-isoleucine + AMP + diphosphate |
- |
? |
6.3.2.26 | L-2-aminoadipate + L-cysteine + L-allo-isoleucine + ATP |
- |
Streptomyces clavuligerus |
L-delta-(aminoadipyl)-L-cysteinyl-D-allo-isoleucine + AMP + diphosphate |
- |
? |