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EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
2.1.1.59	S-adenosyl-L-methionine + CNBr peptide	-	Neurospora crassa	?	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	-	Saccharomyces cerevisiae	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	-	Triticum aestivum	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	-	Neurospora crassa	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	-	Strigomonas oncopelti	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	avian cytochromes c are much better substrates than those from mammalian sources	Triticum aestivum	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	specific for unmethylated cytochrome c	Saccharomyces cerevisiae	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	horse heart cytochrome c-72	Saccharomyces cerevisiae	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	horse heart cytochrome c-72	Triticum aestivum	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?
2.1.1.59	S-adenosyl-L-methionine + cytochrome c L-lysine	horse heart cytochrome c-72	Neurospora crassa	S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine	-	?

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Release 2023.1 (January 2023)