EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.15.1 | (+)-alpha-pinene + putidaredoxin + O2 |
- |
Pseudomonas putida |
(+)-cis-verbenol + (+)-myrtenol + (+)-verbenone + oxidized putidaredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + reduced ferredoxin + O2 |
- |
Novosphingobium aromaticivorans |
(+)-exo-5-hydroxycamphor + oxidized ferredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + reduced ferredoxin + O2 |
- |
Novosphingobium aromaticivorans |
(+)-exo-5-hydroxycamphor + oxidized ferredoxin + H2O |
99% 5-exo-hydroxycamphor by wild-type enzyme and 92% by Y96A mutant |
? |
1.14.15.1 | (+)-camphor + reduced ferredoxin + O2 |
substrate of CYP101D1 and CYP101D2 |
Novosphingobium aromaticivorans |
(+)-exo-5-hydroxycamphor + oxidized ferredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + reduced ferredoxin + O2 |
- |
Novosphingobium aromaticivorans DSM 12444 |
(+)-exo-5-hydroxycamphor + oxidized ferredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + reduced ferredoxin + O2 |
substrate of CYP101D1 and CYP101D2 |
Novosphingobium aromaticivorans DSM 12444 |
(+)-exo-5-hydroxycamphor + oxidized ferredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + O2 + reduced putidaredoxin |
- |
Pseudomonas putida |
(+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + O2 + reduced putidaredoxin |
terminal monooxygenase in a three-component camphor-hydroxylating system from Pseudomonas putida, the reaction cycle requires two distinct electron transfer processes from the [2Fe-2S] containing putidaredoxin to P450cam |
Pseudomonas putida |
(+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + O2 + reduced putidaredoxin |
analysis of protein-protein interactions between enzyme and cofactor, overview |
Pseudomonas putida |
(+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O |
- |
? |
1.14.15.1 | (+)-camphor + O2 + reduced putidaredoxin |
binding of camphor is strongly dependent on the concentration of alcohols, alcohol expels camphor out of the heme cavity of the enzyme by affecting tertiary structure of Cyt P450cam as well as by modifying the solubility properties of camphor in aqueous medium, overview |
Pseudomonas putida |
(+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O |
- |
? |