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Results 31 - 37 of 37

EC Number	Substrates	Commentary Substrates	Organism	Products	Commentary (Products)	Reversibility
1.14.14.29	dehydroepiandrosterone + NADPH + H+ + o2	-	Mus musculus	7alpha-hydroxy-dehydroepiandrosterone + NADP+ + H2O	-	?
1.14.14.29	dehydroepiandrosterone + NADPH + H+ + O2	-	Homo sapiens	? + NADP+ + H2O	-	?
1.14.14.29	dehydroepiandrosterone + NADPH + H+ + O2	-	Sus scrofa	? + NADP+ + H2O	-	?
1.14.14.29	more	both phorbol myristate acetate and cAMP decreases CYP7B1 activity by 60% and 34% respectively, in a time-dependent fashion. Changes in CYP7B1 messenger RNA levels correlate with changes in specific activities. CYP7B1 specific activity is highly regulated but does not seem to be rate limiting for bile acid synthesis	Rattus norvegicus	?	-	?
1.14.14.29	more	regulation of CYP7B1 transcription by Sp1 may play a pivotal role in regulating oxysterol levels, which regulate cholesterol metabolism	Homo sapiens	?	-	?
1.14.14.29	more	the enzyme is regulated by bile acids and cholesterol	Rattus norvegicus	?	-	?
1.14.14.29	more	retinoid-related orphan receptor alpha positively and directly regulates the expression of Cyp7b1	Mus musculus	?	-	?

Results 31 - 37 of 37

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Release 2023.1 (January 2023)