EC Number   |
General Information |
Reference |
|---|
    3.5.1.5 | metabolism |
nitrogen metabolism, could be crucial for the pathogen's survival in nutrient-limited microenvironments where urea is the sole nitrogen source |
719590 |
| 3.5.1.5 | metabolism |
the enzyme catalyses the rapid hydrolysis of urea during the last step of the organic nitrogen mineralization |
-, 734327 |
| 3.5.1.5 | more |
ureases of Canavalia ensiformis are entomotoxic upon the release of internal peptides by insects digestive enzymes |
719594 |
| 3.5.1.5 | physiological function |
Cryptococcus gattii urease plays an important role in virulence, in part possibly through enzyme activity-independent mechanism(s) |
-, 753542 |
| 3.5.1.5 | physiological function |
effects of urease added to rabbit platelets are assessed turbidimetrically. Fluorescein-labelled HPU bound to platelets but not to erythrocytes. HPU induces aggregation of rabbit platelets accompanied by ATP secretion. No correlation is found between platelet activation and ureolytic activity of HPU |
712557 |
| 3.5.1.5 | physiological function |
growth studies demonstrate that Edwardsiella ictaluri is unable to grow at pH 5 in the absence of urea but is able to elevate the environmental pH from pH 5 to pH 7 and grow when exogenous urea is available |
710935 |
| 3.5.1.5 | physiological function |
neutralization of acid by ammonia is essential for gastric Helicobacter pylori colonization |
733789 |
| 3.5.1.5 | physiological function |
the bacterium typically colonizes the mucosal lining of the stomach, where the increase in pH of the strongly acidic environment allows the bacterium that requires pH 6-8 to grow, to persist in the hostile conditions. Concomitantly it incurs damage to the host tissue, thereby giving rise to gastritis and gastroduodenal ulcers. The damaging factors are ammonia and monochloramine |
712785 |
| 3.5.1.5 | physiological function |
the biosynthesis of the active metal-bound form of the nickel-dependent enzyme urease involves the formation of a lysine-carbamate functional group concomitantly with the delivery of two Ni2+- ions into the precast active site of the apoenzyme and with GTP hydrolysis. In the urease system, this role is performed by UreG, an accessory protein belonging to the group of homologous P-loop GTPases |
713483 |
| 3.5.1.5 | physiological function |
the enzyme is a virulence factor for ureolytic bacterial human pathogens, but it is also necessary to convert urea, the most worldwide used fertilizer, into forms of nitrogen that can be taken up by crop plants |
734328 |
