EC Number |
Title |
Organism |
---|
3.4.21.61 | New aromatic compounds from the fruiting body of Sparassis crispa (Wulf.) and their inhibitory activities on proprotein convertase subtilisin/kexin type 9 mRNA expression |
Homo sapiens |
3.4.21.61 | Novel insights into the mechanisms regulating pro-atrial natriuretic peptide cleavage in the heart and blood pressure regulation proprotein convertase subtilisin/kexin 6 is the corin activating enzyme |
Homo sapiens |
3.4.21.61 | Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells |
Homo sapiens |
3.4.21.61 | Proprotein convertase subtilisin/kexin type 6 promotes in vitro proliferation, migration and inflammatory cytokine secretion of synovial fibroblast-like cells from rheumatoid arthritis via nuclear-kappaB, signal transducer and activator of transcription 3 and activator of transcription 3 and extracellular signal regulated 1/2 pathways |
Homo sapiens |
3.4.21.61 | 2.4 A resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor |
Saccharomyces cerevisiae |
3.4.21.61 | A novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 |
Homo sapiens |
3.4.21.61 | A novel domain interaction regulates secretion of proprotein convertase subtilisin/kexin type 9 |
Mus musculus |
3.4.21.61 | A novel splicing variant of proprotein convertase subtilisin/kexin type 9 |
Homo sapiens |
3.4.21.61 | A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake |
Homo sapiens |
3.4.21.61 | A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates |
Macaca fascicularis |