EC Number   |
Reaction |
Reference |
|---|
    6.3.2.8 | ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine |
ligase-catalyzed peptide formation proceeds through an activated acyl-phosphate linkage during the reaction process. ATP assists in this process of the peptide bond formation by donating its gamma-phosphoryl group to activate the carboxyl group of UDP-N-acetylmuramate |
1284 |
| 6.3.2.8 | ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine |
Mur ligase reaction mechanism, overview |
715975 |
| 6.3.2.8 | ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine |
ordered sequential mechanism, with ATP binding first, N-acetylmuramate second, L-Ala third, and ADP being the last product released |
1291 |
| 6.3.2.8 | ATP + UDP-N-acetyl-alpha-D-muramate + L-alanine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine |
the binding order of the substrates can be ATP, UDP-N-acetylmuramate, and Ala |
1292 |
