EC Number   |
Reaction |
Reference |
|---|
   2.1.1.34 | S-adenosyl-L-methionine + guanosine18 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine18 in tRNA |
G18, G19 and the D-stem of the tRNA are required for Gm-methylase recognition |
-, 637162, 637163 |
| 2.1.1.34 | S-adenosyl-L-methionine + guanosine18 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine18 in tRNA |
mechanism, upon binding of guanine 18, a RNA main chain phosphate group activates R41, which then deprotonates the 2'-OH-group for methylation |
663410 |
| 2.1.1.34 | S-adenosyl-L-methionine + guanosine18 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine18 in tRNA |
methylation site |
637164 |
| 2.1.1.34 | S-adenosyl-L-methionine + guanosine18 in tRNA = S-adenosyl-L-homocysteine + 2'-O-methylguanosine18 in tRNA |
substrate recognition sites and mechanism |
-, 637158, 637160, 637161, 637162 |
