EC Number   |
Posttranslational Modification |
Reference |
|---|
   7.2.2.9 | more |
ATP7B in Hep-G2 and HEK-293 cells differ in size, but not in post-translational modifications |
701335 |
| 7.2.2.9 | phosphoprotein |
- |
719946 |
| 7.2.2.9 | phosphoprotein |
ATP7B is phosphorylated in HEK-293 and Hep-G2 cells, overview |
701335 |
| 7.2.2.9 | phosphoprotein |
ATP7B phosphorylation with ATP occurs with diphasic kinetics and is totally copper-dependent |
712378 |
| 7.2.2.9 | phosphoprotein |
both MNK and WND are phosphorylated on serine residues, indicating a key role for one or more serine/threonine kinases for regulation of their trafficking and possibly function |
696595 |
| 7.2.2.9 | phosphoprotein |
Ccc2 N-terminal phosphorylation may be coupled to the ATPase domain catalytic cycle. Protein kinase A phosphorylation site at Ser258 is located between MBD6 and the first transmembrane domain, Cu is predicted to promote Ser258 phosphorylation by increasing solvent accessibility of the region as a consequence of Cu-MBD interactions |
696595 |
| 7.2.2.9 | phosphoprotein |
cisplatin, i.e. cis-diamminedichloroplatinum or DDP, stimulates catalytic phosphorylation of ATP7B |
698990 |
| 7.2.2.9 | phosphoprotein |
copper stimulates both trafficking and phosphorylation of ATP7A, identification of eight in vivo phosphorylation sites in the hamster ATP7A, all clustered within the N- and C-terminal cytosolic domains, C- and N-terminal phosphorylation sites, overview |
712170 |
| 7.2.2.9 | phosphoprotein |
copper stimulates both trafficking and phosphorylation of ATP7A, identification of twenty in vivo phosphorylation sites in the human ATP7A, all clustered within the N- and C-terminal cytosolic domains, eight sites are copper-responsive and hence candidates for regulating copper-responsive trafficking or catalytic activity. A constitutively phosphorylated site is Ser1432, a copper-responsive phosphorylation site Ser1469. Other C-terminal phosphorylation sites are serine residues 1463, 1466, 1469, 1473, 1476 and 1480, C- and N-termninal phosphorylation sites, overview |
712170 |
| 7.2.2.9 | phosphoprotein |
PAA1 is phosphorylated from ATP in the presence of monovalent metals (only CuCl2 and AgNO3). The presence of EGTA does not affect the phosphorylation levels |
719971 |
