EC Number |
Application |
Reference |
---|
5.3.1.6 | medicine |
RPIA is significantly elevated in colorectal. RPIA modulates cell proliferation and oncogenicity via activation of beta-catenin in colon cancer cell lines. RPIA enters the nucleus to form a complex with the adenomatous polyposis coli and beta-catenin, the association protects beta-catenin by preventing its phosphorylation, ubiquitination, and subsequent degradation. The C-terminus of RPIA (amino acids 290 to 311) is necessary for RPIA-mediated tumorigenesis |
749044 |
5.3.1.6 | synthesis |
production of allose from fructose by a one-pot reaction using Flavonifractor plautii D-allulose 3-epimerase and Clostridium thermocellum ribose 5-phosphate isomerase. Under optimal reaction conditions of pH 7.5, 60°C, 0.1 g/l epimerase, 12 g/l isomerase, and 600 g/l fructose in the presence of 1 mM Co2+, 79 g/l allose can be produced within 2 h, with a conversion yield of 13% |
-, 748388 |
5.3.1.6 | synthesis |
production of D-allose from D-psicose by enzyme. At pH 7.5 and 50°C, synthesis of 165 g D-allose per l within 6 h |
678884 |
5.3.1.6 | synthesis |
RpiB is a potential producer of L-form monosaccharides |
717008 |