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EC Number Application Commentary Reference
Show all pathways known for 2.3.1.150Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.150biotechnology increases in pharmaceutical alkaloid content of potential economic significance have been achieved, RNAi suppression is a powerful way to obtain products that poppy does not normally accumulate 689455
Show all pathways known for 2.3.1.150Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.150synthesis coexpression of Papaver somniferum enzymes salutaridine synthase, salutaridine reductase and salutaridinol in Saccharomyces cerevisiae allows for productive spontaneous rearrangement of salutaridinol-7-O-acetate and synthesis of thebaine from (R)-reticuline. A 7-gene pathway for the production of codeine and morphine from (R)-reticuline can be established. Yeast cell feeding assays using (R)-reticuline, salutaridine or codeine as substrates show that all enzymes are functionally coexpressed and that activity of salutaridine reductase and codeine-O-demethylase likely limit flux to morphine synthesis 737076
Show all pathways known for 2.3.1.150Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.150synthesis potential application in biotechnological production of morphine alkaloids 662108
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