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EC Number Application Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.203medicine this methyltransferase is a novel downstream Myctarget which mediates Myc-induced cell proliferation and growth. Therefore, the characterization of hTrm4 substrate specificity can be essential since this enzyme is a potential target for cancer therapies 710135
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.203pharmacology enzymes NSUN2 and METTL1 are implicated in 5-fluorouracil sensitivity in HeLa cells. Interfering with methylation of tRNAs might provide a promising rationale to improve 5-fluorouracil chemotherapy of cancer 737060
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